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Cell Structure and Function
Article . 1999 . Peer-reviewed
Data sources: Crossref
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Translocation of HSP27 and MKBP in Ischemic Heart.

Authors: K, Yoshida; T, Aki; K, Harada; K M, Shama; Y, Kamoda; A, Suzuki; S, Ohno;

Translocation of HSP27 and MKBP in Ischemic Heart.

Abstract

HSP27 and MKBP translocate from the cytosolic to myofibril fraction in ischemic rat heart as demonstrated by immunoblotting. Immunohistochemistry analysis showed that ischemia enhances the Z line labeling of HSP27 and MKBP. Two dimensional gel electrophoresis showed that ischemia increases the hyperphosphorylated form of HSP27. These data suggest that HSP27 and MKBP may be involved in the Z line protection against postischemic reperfusion injury.

Keywords

Male, Time Factors, Myocardium, Immunoblotting, HSP27 Heat-Shock Proteins, Myocardial Ischemia, Immunohistochemistry, Actins, Neoplasm Proteins, Rats, Oxidative Stress, Myofibrils, Animals, Electrophoresis, Gel, Two-Dimensional, Rats, Wistar, Carrier Proteins, Heat-Shock Proteins

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
44
Top 10%
Top 10%
Top 10%
gold