Lamins at a glance

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2012 English Publisher:The Company of BiologistsJournal:Journal of Cell Science, volume 125, pages 2,087-2,093 (issn: 0021-9533, eissn: 1477-9137,

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Authors: Chin Yee, Ho; Jan, Lammerding;

doi: 10.1242/jcs.087288

pmid: 22669459

pmc: PMC3367936

Lamins at a glance

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Abstract

Lamins, the major components of the nuclear lamina, have gained rapidly increasing interest over the past decade as lamin mutations were found to cause numerous devastating diseases. These laminopathies include Emery–Dreifuss muscular dystrophy (EDMD), dilated cardiomyopathy type 1A, limb-girdle

Related Organizations

Cornell University
United States

Keywords

Cell Nucleus, DNA Repair, DNA, Chromatin Assembly and Disassembly, Lamins, Muscular Dystrophies, Alternative Splicing, Xenopus laevis, Progeria, Mutation, Oocytes, Animals, Humans, Protein Isoforms, Protein Multimerization

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