APP at a glance

descriptionPublicationkeyboard_double_arrow_right Article 15 Sep 2007 English Publisher:The Company of BiologistsJournal:Journal of Cell Science, volume 120, pages 3,157-3,161 (issn: 0021-9533, eissn: 1477-9137,

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Authors: Michael S, Wolfe; Suzanne Y, Guénette;

doi: 10.1242/jcs.03481

pmid: 17878232

APP at a glance

- Summary
- Subjects
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Abstract

The characteristic cerebral plaques of Alzheimer disease (AD) are primarily composed of an aggregation-prone 39-43-residue peptide called amyloid β (Aβ), which is a proteolytic product derived from the amyloid β precursor protein (APP), a type I integral membrane protein ([Hardy and Selkoe, 2002

Related Organizations

Brigham and Women's Faulkner Hospital
United States

Keywords

Amyloid beta-Protein Precursor, Alzheimer Disease, Genetic Diseases, Inborn, Mutation, Missense, Animals, Humans, Membrane Proteins, Nerve Tissue Proteins, Protein Structure, Tertiary

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	67
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%