TOR signaling in mammals
Copyright policy )TOR signaling in mammals
Central to the pathways that induce cell growth in mammals is the murine target of rapamycin (mTOR), a multi-domain, 298 kDa, evolutionarily-conserved Ser/Thr kinase that is inhibited by the drug rapamycin ([Schmelzle and Hall, 2000][1]). mTOR exerts its effects by phosphorylating eukaryotic
Enzyme Activation, Phosphatidylinositol 3-Kinases, Multiprotein Complexes, Proto-Oncogene Proteins, TOR Serine-Threonine Kinases, Animals, Protein Serine-Threonine Kinases, Protein Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction
Enzyme Activation, Phosphatidylinositol 3-Kinases, Multiprotein Complexes, Proto-Oncogene Proteins, TOR Serine-Threonine Kinases, Animals, Protein Serine-Threonine Kinases, Protein Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction
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