New trends in cellular therapy

descriptionPublicationkeyboard_double_arrow_right Article 15 Sep 2020 English Publisher:The Company of BiologistsJournal:Development, volume 147 (issn: 0950-1991, eissn: 1477-9129,

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Authors: Hideyuki Okano; Doug Sipp;

doi: 10.1242/dev.192567

pmid: 32943426

New trends in cellular therapy

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Abstract

ABSTRACT Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.

Related Organizations

Keio University
Japan
RIKEN Center for Advanced Intelligence Project
Japan
RIKEN Center for Biosystems Dynamics Research
Japan

Keywords

Clinical Trials as Topic, Induced Pluripotent Stem Cells, Cell- and Tissue-Based Therapy, Animals, Humans, Regenerative Medicine

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