In the ideal, research would always be transformative, yielding information that immediately and directly improves not just a discipline-specific knowledge base but the human condition as well. In the real world, of course, research represents an accumulation of experiences and incremental gains, which together ultimately reveal what we really want to know. Conducting research is most often like putting together the pieces of a 1,000-plus–piece puzzle: each one seems to contribute just a little information to the whole, but if any one of those pieces is missing, the picture is incomplete. Neuro-Oncology is a journal that serves both a large constituency (those interested and involved in the umbrella concept of “neuro-oncology”) and those working in the subspecialties that individually contribute information to the whole. With the rise in our impact factor and our now one-year-old practice of bimonthly publication, submissions to the journal and the quality of those submissions are at an all-time high. One of the more difficult tasks for journal editors (and the peer reviewers who provide critiques on the submissions) is to determine which manuscripts merit publication. The hard truth is that sometimes even good papers, those that in themselves describe robust results gained from well-designed inquiries, may not make it into our pages—whether because of space constraints, timeliness, or the scope of content.