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Alopecia induced by dopamine agonists

Authors: Rowena E. Tabamo; Alessandro Di Rocco;

Alopecia induced by dopamine agonists

Abstract

We report two women with PD who developed alopecia while being treated with the dopamine agonists pramipexole and ropinirole. The alopecia reversed partially after the drugs were discontinued. Both women were postmenopausal and had no history of hair loss or other dermatologic disorders. Reversible alopecia has been described in patients treated with bromocriptine, pergolide, or levodopa, but not in association with other dopaminergic drugs.1-5⇓⇓⇓⇓ ### Patient 1. Patient 1 was a 66-year-old woman with an unremarkable medical history and no history of drug allergy. She was first diagnosed with PD at age 63, when she presented with left hand rest tremor and left leg cramping. Soon after her diagnosis, she began taking selegiline 5 mg twice a day and amantadine 100 mg three times a day. Selegiline was discontinued a year later because of orthostatic hypotension. She continued taking amantadine only for 2 years, when pramipexole was started and brought to a maintenance dosage of 1.5 mg per day with improvement of her parkinsonian symptoms and no significant side effects. She was taking no other medication except for vitamin supplements and occasionally, stool softeners. Less than 2 months after …

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Keywords

Indoles, Alopecia, Parkinson Disease, Antiparkinson Agents, Thiazoles, Pramipexole, Dopamine Agonists, Humans, Female, Benzothiazoles, Aged

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
20
Average
Top 10%
Top 10%
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