The Biology of Vascular Endothelial Growth Factor
Copyright policy )The Biology of Vascular Endothelial Growth Factor
The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1. Neovascularization (angiogenesis) is also implicated in the pathogenesis of a number of disorders. These include: proliferative retinopathies, age-related macular degeneration, tumors, rheumatoid arthritis, and psoriasis1,2. A strong correlation has been noted between density of microvessels in primary breast cancers and their nodal metastases and patient survival3. Similarly, a correlation has been reported between vascularity and invasive behavior in several other tumors4–6.
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Vascular Endothelial Growth Factor A, Lymphokines, Neovascularization, Pathologic, Vascular Endothelial Growth Factors, Molecular Sequence Data, Neovascularization, Physiologic, Receptor Protein-Tyrosine Kinases, Endothelial Growth Factors, Receptors, Vascular Endothelial Growth Factor, Gene Expression Regulation, Neoplasms, Humans, Receptors, Growth Factor, Amino Acid Sequence, RNA, Messenger, Signal Transduction
Vascular Endothelial Growth Factor A, Lymphokines, Neovascularization, Pathologic, Vascular Endothelial Growth Factors, Molecular Sequence Data, Neovascularization, Physiologic, Receptor Protein-Tyrosine Kinases, Endothelial Growth Factors, Receptors, Vascular Endothelial Growth Factor, Gene Expression Regulation, Neoplasms, Humans, Receptors, Growth Factor, Amino Acid Sequence, RNA, Messenger, Signal Transduction
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