
doi: 10.1201/b22030-91
handle: 11336/149227
This chapter provides state-of-the-art overviews on foodborne diseases caused by Trichothecenes in relation to their etiology, biology, epidemiology, clinical presentation, pathogenesis, diagnosis, treatment, and prevention. Trichothecenes are sesquiterpenes whose biosynthesis proceeds from the farnesyl pyrophosphate route. Trichothecenes are synthesized by a complex metabolic route that begins with a sesquiterpene cyclization and involves a series of up to eight oxygenations and four esterifications. The acute phytotoxicity of trichothecenes, their production in infected plant tissues, and their production by plant-pathogenic fungi all provided evidence of a role for trichothecenes in plant disease. Trichothecenes act as translational inhibitors, suppress the defense response in host plants, and keep the plant from sealing the diseased tissue. Although acute outbreaks associated with human exposition to trichothecenes are uncommon, these compounds have been implied in a small number of epidemic diseases since their discovery.
Fil: Mourelos, Cecilia Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Biológicas. Centro de Investigaciones de Fitopatología. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones de Fitopatología; Argentina
Fil: Girotti, Juan Roberto. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Biológicas. Centro de Investigaciones de Fitopatología. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones de Fitopatología; Argentina
Fil: Malbrán, Ismael. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Biológicas. Centro de Investigaciones de Fitopatología. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones de Fitopatología; Argentina
Fil: Lori, Gladys. No especifíca;
MYCOTOXINS, FUSARIUM, FOOD, https://purl.org/becyt/ford/4.1, https://purl.org/becyt/ford/1.4, https://purl.org/becyt/ford/4, https://purl.org/becyt/ford/1
MYCOTOXINS, FUSARIUM, FOOD, https://purl.org/becyt/ford/4.1, https://purl.org/becyt/ford/1.4, https://purl.org/becyt/ford/4, https://purl.org/becyt/ford/1
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