Allergen immonotherapy in historical perpective definition of an allergen aerobiology allergen nomenclature tree pollen allergens grass pollen allergens weed pollen allergens mold allergens biting insect allergens mite allergens cockroach and other inhalent insect allergens food allergens latex allergens drug allergens, haptens and anaphylatoxins manufacturing and standardizing allergen extracts alergen extract unitage and its clinical significance immunologic responses to immunotherapy efficacy - clinical responses to immunotherapy patient selection for allergen immunotherapy preparing and mixing office extracts administering of inhalent allergenic extracts administering hymenoptera venom and biting insect pharmacoeconomic considerations for allergen immunotherapy potential new forms of immunotherapy recominant allergens, a new form of immunotherapy? unproven and controversial forms of immunotherapy in vitro tests to monitor efficacy of immunotherapy in IgE medicated disease parameters to monitor clinical efficiacy of immunotherapy in IgE medicated disease preventing adverse effects and fatalities associated with allergen skin testing and immunotherapy treatment of anaphylaxis and anaphylactoid reactions suggested forms for use during skin testing and immunotherapy.