
pmid: 7383713
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells. The importance of complement in the destruction of IgM-coated cells has also been recognized.
Male, Erythrocytes, Adolescent, Infant, Complement System Proteins, Penicillins, Antigen-Antibody Reactions, Immunoglobulin M, Adrenal Cortex Hormones, Child, Preschool, Immunoglobulin G, Humans, Female, Anemia, Hemolytic, Autoimmune, Complement Pathway, Classical, Methyldopa, Child, Haptens, Immunosuppressive Agents, Autoantibodies
Male, Erythrocytes, Adolescent, Infant, Complement System Proteins, Penicillins, Antigen-Antibody Reactions, Immunoglobulin M, Adrenal Cortex Hormones, Child, Preschool, Immunoglobulin G, Humans, Female, Anemia, Hemolytic, Autoimmune, Complement Pathway, Classical, Methyldopa, Child, Haptens, Immunosuppressive Agents, Autoantibodies
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