ONTOGENESIS AND MORPHOLOGY OF THE CHOROID PLEXUS Development of the Blood-Cerebrospinal Fluid Barrier, C. Joakim Ek, Katarzyna M. Dziegielewska, and Norman R. Saunders Normal and Pathologically Altered Structures of the Choroid Plexus, Lise Prescott, and Milton W. Brightman Junctional Proteins of the Blood-CSF Barrier, Susanne Angelow, and Hans-Joachim Galla PHYSIOLOGY AND MOLECULAR BIOLOGY OF THE BLOOD-CSF BARRIER Fluid Compartments of the Central Nervous System, Malcolm B. Segal Peptide-Mediated Regulation of CSF Formation and Blood Flow to the Choroid Plexus, Joanna Szmydynger-Chodobska and Adam Chodobski Ion Transporters and Channels Involved in CSF Formation. Peter D. Brown, Tracey Speake, Sarah L. Davies, and Ian D. Millar Molecular Basis of Xenobiotic Transport and Metabolism in Choroid Plexus, David S. Miller, Simon Lowes, and John B. Pritchard Homeostasis of Nucleosides and Nucleobases in the Brain: The Role of Flux Between the CSF and the Brain ISF, Transport Across the Choroid Plexus and the Blood-Brain Barrier, and Cellular Uptake, Zoran B. Redzic Regulation of Neuroactive Metals by the Choroid Plexus, G. Jane Li and Wei Zheng The Role of the Choroid Plexus in Transport and Production of Polypeptides, Adam Chodobski, Gerald D. Silverberg, and Joanna Szmydynger-Chodobska Expression of Transthyretin in the Choroid Plexus: Relation to the Brain Homeostasis of Thyroid Hormones, Samantha J. Richardson BLOOD-CSF BARRIER IN DISEASES Choroid Plexus and CSF in Alzheimer's Disease: Altered Expression and Transport of Proteins and Peptides, Conrad E. Johanson, Gerald D. Silverberg, John E. Donahue, John A. Duncan, and Edward G. Stopa The Blood-CSF Barrier and Cerebral Ischemia, Richard F. Keep, Steven R. Ennis, and Jianming Xiang Ageing of the Choroid Plexus and CSF System: Implications for Neurodegeneration, Jane E. Preston, Michael R. Wilson, and Ruo Li Chen The Role of the Choroid Plexus in HIV-1 Infection, Carol K. Petito Choroid Plexus and Drug Therapy for Neuro-AIDS, Julie E. Gibbs and Sarah A. Thomas Blood-CSF Barrier in Iron Regulation and Manganese-Induced Parkinsonism, Wei Zheng The Involvement of the Choroid Plexus and the Cerebrospinal Fluid in Immune Molecule Signaling in the CNS, Miles Herkenham Experimental Models of Hydrocephalus: Relation to Human Pathology, Charles E. Weaver and John A. Duncan, III Clinical Aspects of Disorders of the Choroid Plexus and the CSF Circulation, John D. Pickard, Marek Czosnyka, N. Higgins, B. Owler, S. Momjian, and Alonso Pena Grafting of the Choroid Plexus: Clinical Implications, Naoya Matsumoto, Yutaka Itokazu, Masaaki Kitada, Shushovan Chakrabortty, Kazushi Kimura, and Chizuka Ide CURRENT IN VIVO AND IN VITRO MODELS OF THE BLOOD-CSF BARRIER In situ Techniques Used in the Blood-CSF Barrier Research, Wei Zheng and Malcolm B. Segal In vitro Investigation of the Blood-Cerebrospinal Fluid Barrier Properties. Primary Cultures and Immortalized Cell Lines of the Choroidal Epithelium, Nathalie Strazielle and Jean-Francois Ghersi-Egea In vivo Techniques Used in the Blood-CSF Barrier Research: Measurement of CSF Formation, Adam Chodobski and Malcolm B. Segal