Historical perspective, Thomas J. Dougherty, et al. Part 1 Molecular and cellular effects of photodynamic therapy: fluorescence and photodynamic effects of phthalocyanines and porphyrins in cells, Johan Moan, et al photodynamic therapy - membrane and enzyme photobiology, Tom M.A.R. Dubbleman, et al cellular targets of photodynamic therapy as a guide to mechanisms, Russell Hilf cellular stress responses following photodynamic therapy, Stefan W. Ryter, et al basic photobiology and mechanisms of action of phthalocyanines, Ehud Ben-Hur cationic sensitizers, combination therapies, and new methodologies, Allan R. Oseroff bacterial and viral photodynamic inactivation, Zvi Malik, et al. Part 2 Tissue effects of photodynamic therapy: determinants for photodynamic tissue destruction, David A. Bellnier and Barbara W. Henderson photosensitizing dyes related to hematoporphyrin derivative - structure-activity relationships, David Kessel, et al phthalocyanines and related compounds - structure activity relationships, Benoit Paquette and Johan E. van Lier reduced porphyrins as photosensitizers - synthesis and biological effects, Alan R. Morgan low density lipoproteins-liposome delivery systems for tumour photosensitizers in vivo, Giulio Jori photosensitizer delivery mediated by macro-molecular carrier systems, Tayyaba Hasan normal tissue damage following photodynamic therapy - are there biological advantages?, Hugh Barr and Stephen G. Bown. Part 3 Clinical applications of photodynamic therapy: clinical photodynamic therapy - the continuing evolution, Stuart L. Marcus photodynamic therapy in treatment of early cancer, Yoshihiro Hayata and Harubumi Kato palliation for endobronchial tumours in lung cancer, Anne-Marie Regal innovative photodynamic therapy at the National Cancer Institute - intraoperative, intracavitary treatment, Harvey I. Pass and Thomas F. DeLaney clinical application of photodynamic therapy - German collaborative studies, Kieter Jocham, et al photodynamic therapy - an eight-year experience, James S. McCaughan, et al. Part 4 Photophysics and photodynamic therapy technology: light delivery and optical dosimetry in photodynamic therapy of solid tumours, Willem M. Star, et al the implications of photobleaching for photodynamic therapy, Lars O. Svaasand and William R. Potter laser spectroscopy in medical diagnostics, Stefan Andersson-Engels, et al.