Nuclear Magnetic Resonance (NMR) II. Imaging in Dementia

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1985 English Publisher:Royal College of PsychiatristsJournal:British Journal of Psychiatry, volume 146, pages 31-35 (issn: 0007-1250, eissn: 1472-1465,

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Authors: J A, Besson; F M, Corrigan; E I, Foreman; L M, Eastwood; F W, Smith; G W, Ashcroft;

doi: 10.1192/bjp.146.1.31

pmid: 2983817

Nuclear Magnetic Resonance (NMR) II. Imaging in Dementia

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Abstract

SummaryProton NMR imaging of the brain is rapidly becoming established as a useful investigative tool in medicine. This paper examines the usefulness of the NMR parameters—spin-lattice relaxation time (T1) and proton density (PD)—in differentiating groups of patients with senile dementia of Alzheimer type (SDAT) and multi-infarct dementia (MID) from each other, and from elderly controls. T1 values increase with severity of dementia. NMR parameters may also be of use in localising regions of brain damage.

Related Organizations

NHS Grampian
United Kingdom
University of Aberdeen
United Kingdom
Aberdeen Royal Infirmary
United Kingdom

Keywords

Diagnosis, Differential, Magnetic Resonance Spectroscopy, Alzheimer Disease, Brain, Humans, Water, Dementia, Protons, Aged

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