This paper reports and discusses the occurrence of transvestism in three members of the same family, over two generations. No similar series of cases has been found in the literature. Lukianowicz, in his survey of the subject, mentions two cases in which there was a suspicion of transvestite tendencies in another member of the family. Taylor and McLachlan mention that two brothers of one transvestite in their series were said to have symptoms similar to those of the patient. They located one of the two, but decided not to include him in their series because “his cross-dressing was not without strong and persistent criminal motives. He posed as a prostitute and carried a weapon with him to assault his ‘customers' before robbing them.”