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Synthesis of aromatic lactone analogues of Lipoxin A4

descriptionPublicationkeyboard_double_arrow_right Article 09 Feb 2022 Norway English Publisher:Springer Science and Business Media LLCJournal:BMC Research Notes, volume 15 (eissn: 1756-0500, Copyright policy )
Authors: Aya Ismael; Muhammad Zeeshan; Jørn H. Hansen;

doi: 10.1186/s13104-022-05917-4

pmid: 35139886

pmc: PMC8827294

handle: 10037/26125

Synthesis of aromatic lactone analogues of Lipoxin A4

Abstract

AbstractObjectiveSynthesis of novel aromatic Lipoxin A4 lactone analogues.ResultsNovelpara-substituted aromatic lactone analogues of Lipoxin A4 have been synthesized in a convergent manner with six steps in the longest linear sequence in 12–13% yields, employing 2-deoxy-d-ribose as a chiral pool starting material and the classicalE-selective Wittig olefination.

Country
Norway
Related Organizations
Keywords

Science (General), QH301-705.5, R, Lipoxins, Q1-390, Research Note, Lactones, Lipoxin analogues, Aromatics, Medicine, Wittig olefination, Biology (General)

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    selected citations
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    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Top 10%
Average
Average
Green
gold
Related to Research communities
UArctic