Lactate clearance: the earlier the better?

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2008 English Publisher:Springer Science and Business Media LLCJournal:Critical Care, volume 12, page P451 (issn: 1364-8535,

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Authors: Guiotto, G; Schiraldi, F; Paladino, F; Verde, S; Antonaglia, V;

doi: 10.1186/cc6672

Lactate clearance: the earlier the better?

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Abstract

In cardiorespiratory failure there is an oxygen-metabolism imbalance mirrored in a timely fashion by a rise in blood lactate associated with a lowering of blood pH. If the therapeutic approach were able to repay this oxygen debt and to restore an adequate blood flow to the lactate-remover organs, effective lactate clearance (LC) should be observed. The study aim was to evaluate whether a short-term (2 hour) LC could be used as a prognostic marker to tailor the therapy in cardiorespiratory insufficiencies.

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