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Abstract The differential diagnosis between idiopathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis(IPF)/usual interstitial pneumonia(UIP)is tough in both clinicians and pathologists. In this study, we analyzed the lesions of right lung removed from a 58-year-old patient by gross and microscopy. The results showed that the pathological appearance of nonspecific interstitial pneumonia (NSIP) and UIP coexisted in his upper lobe. Besides, because of severe fibrosis in middle and lower lobes, it was hard to distinguish the lesions of NSIP fibrotic pattern (NSIP-F) or UIP. Based on clinic-radiologic-pathological data, the diagnosis of INSIP-F was made for this patient finally. Our study suggests that UIP is not always an accurate diagnosis when the NSIP and UIP coexist, and NSIP can have regions of UIP. Virtual slide The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2573531681608730
Male, Histology, Biopsy, Case Report, Severity of Illness Index, Pathology and Forensic Medicine, Idiopathic nonspecific interstitial pneumonia, Fatal Outcome, Diagnosis, Pathology, RB1-214, Humans, Usual interstitial pneumonia, Pneumonectomy, Lung, Metaplasia, Nonspecific interstitial pneumonia, Fibroblasts, Middle Aged, Idiopathic Pulmonary Fibrosis, Treatment Outcome, Autopsy, Lung Diseases, Interstitial, Tomography, X-Ray Computed
Male, Histology, Biopsy, Case Report, Severity of Illness Index, Pathology and Forensic Medicine, Idiopathic nonspecific interstitial pneumonia, Fatal Outcome, Diagnosis, Pathology, RB1-214, Humans, Usual interstitial pneumonia, Pneumonectomy, Lung, Metaplasia, Nonspecific interstitial pneumonia, Fibroblasts, Middle Aged, Idiopathic Pulmonary Fibrosis, Treatment Outcome, Autopsy, Lung Diseases, Interstitial, Tomography, X-Ray Computed
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 8 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |