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Diagnostic Pathology
Article . 2012 . Peer-reviewed
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Diagnostic Pathology
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Other literature type . 2012
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Diagnostic Pathology
Article . 2012
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Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?

Authors: Xianghua Yi; Xuyou Zhu; Suxia Zhang; Xia Fang; Fang Liu; Gelin Jiang; Huiping Li; +3 Authors

Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis?

Abstract

Abstract The differential diagnosis between idiopathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis(IPF)/usual interstitial pneumonia(UIP)is tough in both clinicians and pathologists. In this study, we analyzed the lesions of right lung removed from a 58-year-old patient by gross and microscopy. The results showed that the pathological appearance of nonspecific interstitial pneumonia (NSIP) and UIP coexisted in his upper lobe. Besides, because of severe fibrosis in middle and lower lobes, it was hard to distinguish the lesions of NSIP fibrotic pattern (NSIP-F) or UIP. Based on clinic-radiologic-pathological data, the diagnosis of INSIP-F was made for this patient finally. Our study suggests that UIP is not always an accurate diagnosis when the NSIP and UIP coexist, and NSIP can have regions of UIP. Virtual slide The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2573531681608730

Related Organizations
Keywords

Male, Histology, Biopsy, Case Report, Severity of Illness Index, Pathology and Forensic Medicine, Idiopathic nonspecific interstitial pneumonia, Fatal Outcome, Diagnosis, Pathology, RB1-214, Humans, Usual interstitial pneumonia, Pneumonectomy, Lung, Metaplasia, Nonspecific interstitial pneumonia, Fibroblasts, Middle Aged, Idiopathic Pulmonary Fibrosis, Treatment Outcome, Autopsy, Lung Diseases, Interstitial, Tomography, X-Ray Computed

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    8
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
8
Average
Average
Average
Green
gold