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European Respiratory Journal
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European Respiratory Journal
Article . 2019 . Peer-reviewed
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Utrecht University, University Medical Center Utrecht
Article . 2019
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European Respiratory Journal
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Full-Text: https://syndication.highwire.org/content/doi/10.1183/13993003.02379-2018
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European Respiratory Journal
Article . 2020
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https://dx.doi.org/10.1183/139...
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European Respiratory Journal
Article . 2019 . Peer-reviewed
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Intestinal organoids to model cystic fibrosis

descriptionPublicationkeyboard_double_arrow_right Article 25 Apr 2019 Netherlands English Publisher:European Respiratory Society (ERS)Journal:European Respiratory Journal, volume 54, page 1,802,379 (issn: 0903-1936, eissn: 1399-3003, Copyright policy )Funded by:EC | HIT-CF
Authors: van Mourik, Peter; Beekman, Jeffrey M.; van der Ent, Cornelis K.;

doi: 10.1183/13993003.02379-2018

pmid: 31023844

Intestinal organoids to model cystic fibrosis

Abstract

CF can be studied using patient-specific intestinal organoids. CFTR protein function in intestinal organoids correlates with clinical disease severity and drug testing in organoids could aid in finding drugs for people with rare CFTR mutations.https://bit.ly/2GryRl0

Country
Netherlands
Related Organizations
Keywords

Pulmonary and Respiratory Medicine, Cystic Fibrosis, Primary Cell Culture, Cystic Fibrosis Transmembrane Conductance Regulator, Organoids, Animals, Humans, Biological Assay, Mutant Proteins, Intestinal Mucosa

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 43
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
43
Top 10%
Top 10%
Top 10%
bronze
Funded by
Related to Research communities
Knowmad Institut
Netherlands Research Portal