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Blood
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Blood
Article . 2013 . Peer-reviewed
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Blood
Article . 2013
Data sources: Europe PubMed Central
Blood
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PARP1 is required for chromosomal translocations

descriptionPublicationkeyboard_double_arrow_right Article 23 May 2013Publisher:American Society of HematologyJournal:Blood, volume 121, pages 4,359-4,365 (issn: 0006-4971, eissn: 1528-0020, Copyright policy )
Authors: Christopher R. Cogle; Jac A. Nickoloff; Yuehan Wu; David M. Weinstock; Lijian Shao; Virginia M. Klimek; Elizabeth A. Williamson; +8 Authors

doi: 10.1182/blood-2012-10-460527

pmid: 23568489

pmc: PMC3663429

PARP1 is required for chromosomal translocations

Abstract

Key Points Chromosomal translocations are mediated by PARP1 and can be suppressed by the clinical PARP1 inhibitors.

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Keywords

Indoles, Leukemia, Poly (ADP-Ribose) Polymerase-1, Fibroblasts, Poly(ADP-ribose) Polymerase Inhibitors, Piperazines, Translocation, Genetic, Acute Disease, Humans, Phthalazines, DNA Breaks, Double-Stranded, Poly(ADP-ribose) Polymerases, RNA, Small Interfering, Cells, Cultured

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 69
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
69
Top 10%
Top 10%
Top 10%
bronze