Abstract : As a result of the proliferation of benzene solutions in several procuction technologies and prolonged exposure poisonings, the question about skin as a way of absorption has re-emerged with respect to the direction of preventive measures and the necessity to clarify the observed clinical signs of absorption. The absorption of benzene throughout the skin in men in experimental conditions was examined. The liquid benzene was absorbed with the velocity about 0,4 mg/sq cm/hour; the absorption of the benzene vapors was insignificant and it did not exceed 1 per cent of this absorbed throughout the respiratory ways in the same conditions. The study was based on the determination of phenol contents in urine and on the new direct chemical method for the designation of skin absorption of benzene, this method was described in the paper. The authors concluded that the absorption of benzene, this method was described in the paper. The authors concluded that the absorption of benzene throughout the skin must not be neglected.