<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Lysosomes, Lysosomal Storage Diseases, and Inflammation

Name: Lysosomes, Lysosomal Storage Diseases, and Inflammation
Creator: Simonaro, Calogera M.
Keywords: 0301 basic medicine, Medicine (General), 0303 health sciences, 03 medical and health sciences, R5-920, inflammation, lysosomal storage disorders, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 14 May 2016Publisher:FapUNIFESP (SciELO)Journal:Journal of Inborn Errors of Metabolism and Screening, volume 4, page 232,640,981,665,046 (issn: 2326-4098, eissn: 2326-4594,

Authors: Simonaro, Calogera M.;

doi: 10.1177/2326409816650465

Lysosomes, Lysosomal Storage Diseases, and Inflammation

- Summary
- Subjects
- Metrics

Abstract

Lysosomes were originally described in the early 1950s by de Duve who was also the first to recognize the importance of these organelles in human disease. We know now that lysosomes are involved in numerous biological processes, and abnormalities in lysosomal function may result in a broad range of diseases. This review will briefly discuss the role of lysosomes in inflammation and how disruption of normal lysosomal function in the lysosomal storage diseases (LSDs) leads to abnormalities in inflammation and immunity.

Related Organizations

Icahn School of Medicine at Mount Sinai
United States

Keywords

Medicine (General), R5-920, inflammation, lysosomal storage disorders

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	34
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%