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Influence of Radiofrequency Catheter Ablation on Platelet Aggregation

Authors: Jurate Cimbolaityte; Aras Puodziukynas; Ausra Mongirdiene; Tomas Kazakevičius; Pranas Grybauskas; Julius Ptasekas; Vilma Kozlovaite;

Influence of Radiofrequency Catheter Ablation on Platelet Aggregation

Abstract

the objective of this article was to find out how radiofrequency catheter ablation (RFA) influences platelet aggregation (PA), and the dependence on the total energy (TE) of RFA used and the cause of arrhythmia. We investigated 97 patients. PA was analyzed before, after, and in 24 hours after RFA. ADP- and epinephrine-induced PA significantly decreased after RFA by 5% and 8.9% ( P < .001), respectively, and increased in 24 hours close to baseline. PA induced by ADP and collagen did not radically depend on the TE. Epinephrine-induced PA decreased after RFA by 0%, 8% ( P < .05), and 16.9% ( P < .01) in groups of patients where the TEs used were <4000 J, 4000 to 15 000 J, and >15 000 J, respectively. There were no significant differences in PA between groups based on the cause of arrhythmia. ADP- and epinephrine-induced PA significantly decreased after RFA and returned close to baseline in 24 hours. Epinephrine-induced PA was inversely associated with the TE used for RFA.

Keywords

Adult, Male, Epinephrine, Platelet Aggregation, Arrhythmias, Cardiac, In Vitro Techniques, Middle Aged, Adenosine Diphosphate, Thromboembolism, Catheter Ablation, Humans, Female, Collagen, Aged

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold