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Surface Patterning of Gram Positive and Gram Negative Bacterial Cells Using a Small Hydrophobic Molecule

Authors: Pathak, Srikant; Simmons, Blake A.; Chhabra, Swapnil R.; McElhanon, James R.; Dentinger, Paul M.;

Surface Patterning of Gram Positive and Gram Negative Bacterial Cells Using a Small Hydrophobic Molecule

Abstract

A facile novel approach for patterning Escherichia coli(a gram negative bacterium) and Bacillus subtilis (a gram positive bacterium) using a patterned template of Glycidyl 4-nonylphenyl ether (GNPE) is reported. Highly specific cell patterns with high cell-viability rates (over 85%) were obtained in each case. Cell coverage density was found to be proportional to GNPE concentration over identical surface areas. The versatility of the approach to immobilize both gram positive and gram negative bacterial cells using the same hydrophobic molecule highlights its potential in numerous cell array applications.

Country
Australia
Related Organizations
Keywords

Biomaterials, Photolithography, Cell-patterning, 2208 Electrical and Electronic Engineering, Cell-viability, and Optics, 3107 Atomic and Molecular Physics, and Optics, 3107 Atomic and Molecular Physics, Surface chemistry

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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