Background. The search for personality traits that are outstanding predictors of hardiness is a widespread research task. However, research results are difficult to access due to the variety of personality characteristics studied. Overcoming this situation involves the use of universal models of personality traits, which include the Big Five model. Objective. Analysis of the relationship between the traits of the Big Five and the hardiness level of a person. Study Participants. The sample consisted of 808 respondents (46.2% men and 53.8% women) aged 17 to 82. Methods. The empirical data were collected by: the questionnaire “Hardiness Survey” adapted by D.A. Leontiev and E.I. Rasskazova; the short questionnaire of the Big Five adapted by A.S. Sergeeva, B.A. Kirillov, and A.F. Dzhumagulova. Mathematical processing of the research results included methods of descriptive statistics, correlation analysis, regression analysis and one-factor analysis of variance. Results. Correlations were found between the total index of hardiness and its components and four traits of the Big Five, such as extroversion, conscientiousness, emotional stability and openness. In addition, the indicator of commitment demonstrated the relationship with agreeableness as a factor of the Big Five (p ≤ 0.05). Regression analysis (R2 = 0.28) allowed us to state that significant predictors of hardiness are extraversion (β = 0.17), emotional stability (β = 0.19) and conscientiousness (β = 0.20). Conclusions. The results of the study can be used in the development of psychological intervention programmes aimed at promoting the stress resistance of young people, adults and the elderly. The prospects of the study are associated with a detailed study of the relationship between resilience and the factors of the Big Five, taking into account various socio-demographic factors.