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Methods of Information in Medicine
Article . 2007 . Peer-reviewed
Data sources: Crossref
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Right Ventricular Assistance by Continuous Flow Device

A Numerical Simulation
Authors: De Lazzari C; Ferrari G;

Right Ventricular Assistance by Continuous Flow Device

Abstract

Summary Objectives·. This work is another step in the development of the circulatory model CARDIOSIM® and of its model library. Continuous flow assistance is often used to support the right ventricular failure. Computer simulation is one of the methods to study the effect of this assistance on the failing ventricle. The purpose of this study was to evaluate the effect of this support on some hemodynamic variables, when different right ventricular end-systolic elastance and pump speed values were applied. Methods: The rotary blood pump model was included into the software package CARDIOSIM®, which reproduces the cardiovascular system. Lumped parameters models were used to reproduce the circulatory phenomena. Variable elastance models reproduced the Starling’s law of the heartfor both ventricles. In the study right ventricular end-systolic elastance (EmaxraT) and the rotational speed of the pumptookthree different values. All the other parameters of the model were constants. Results: The rotational speed of the pump had a significant influence on right ventricular end-diastolic and end-systolic volumes, right atrial pressure (Pra), right ventricular (Qro) and pump flows. The effects on pulmonary arterial pressure (Pap) were more evident when the right ventricular end-systolic elastance was low. When the speed of the device increased the mean value of Pra decreased for each value of EmaxMT. The total flow (Qro + pump flow) increased when the speed of the pump increased. Conclusions: Our simulation (in good agreement with the results presented in literature) showed that Hemo-pump produces a rise in total flow, a drop in blood flow pumped out by the right ventricle and a drop in right atrial pressure.

Country
Italy
Keywords

Systole, Heart Ventricles, Blood Pressure, Models, Theoretical, Cardiovascular System, Cardiovascular Physiological Phenomena, Cardiovascular system, Diastole, Heart Rate, Humans, Computer Simulation, Right ventricular assist device, Heart-Assist Devices, Software

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
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