
doi: 10.1159/000473204
pmid: 7202450
7 children, 20 months to 11 years old, with cystinuria and renal calculi were studied. Surgical treatment and alpha-mercaptopropionylglycine (MPG) gave satisfactory results in 5 children. The causes of the recurrences in the other 2 children are discussed. MPG therapy is effective but can cause a nephrotic syndrome at a dose of more than 50 mg/kg/day. A cystinuria of less than 200 mg/day cannot always be considered safe in children. The alkalinization and dilution of urine remain extremely important in the treatment of cystinuria.
Male, Cystinuria, Nephrotic Syndrome, Tiopronin, Infant, Amino Acids, Sulfur, Kidney Calculi, Recurrence, Child, Preschool, Humans, Female, Child
Male, Cystinuria, Nephrotic Syndrome, Tiopronin, Infant, Amino Acids, Sulfur, Kidney Calculi, Recurrence, Child, Preschool, Humans, Female, Child
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