Malignant Transformation of Hepatocellular Adenoma

descriptionPublicationkeyboard_double_arrow_right Article 17 Dec 2016 English Publisher:S. Karger AGJournal:Oncology, volume 92, pages 16-28 (issn: 0030-2414, eissn: 1423-0232,

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Authors: Wing Yee Kwok; Satoru Hagiwara; Naoshi Nishida; Tomohiro Watanabe; Toshiharu Sakurai; Hiroshi Ida; Yasunori Minami; +14 Authors

doi: 10.1159/000451012

pmid: 27988517

Malignant Transformation of Hepatocellular Adenoma

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Abstract

The patient was a 20-year-old male in whom a hepatic hypervascular mass accompanied by intratumoral hemorrhage was detected on examination for epigastric pain. Based on the enlargement of the mass and diagnostic imaging, hepatocellular adenoma (HCA) was suspected and hepatectomy was performed. The lesion was diagnosed as malignant transformation of β-catenin-activated HCA. There are only few reports of cases with malignant transformation of HCA in Japan; it is necessary to accumulate cases to investigate it.

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Keywords

Adult, Male, Young Adult, Cell Transformation, Neoplastic, Liver Neoplasms, Humans, Adenoma, Liver Cell

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