Optical coherence tomography (OCT) angiography (OCT-A) represents an innovative imaging technique which can delineate the retinal and choroidal vascular networks. OCT-A in the assessment of chorio-retinal dystrophies reveal alterations especially located at the level of the deep capillary plexus and the choriocapillaris. This information can have a direct implication on the understanding of the pathogenesis of dystrophies and for their future therapeutic management.