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Features of DIC in Dengue Hemorrhagic Fever

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article 16 Apr 2015Publisher:S. Karger AG

Authors: Yoshinori Funahara; Riadi Wirawan; Sumarmo;

doi: 10.1159/000408460

pmid: 6667246

Features of DIC in Dengue Hemorrhagic Fever

- Summary
- Subjects
- Metrics

Abstract

Collaborative studies on hemostasis in dengue hemorrhagic fever (DHF) patients by Indonesian and Japanese teams revealed that all DHF patients had manifestations of the acute type of disseminated intravascular coagulation (DIC). Prolongations of activated partial thromboplastin time and prothrombin time and decreases of platelet counts, fibrinogen, prothrombin, factor VIII, plasminogen and antithrombin III activities were observed transiently during the acute stage of DHF. It was also found that alpha 2 antiplasmin was decreased in the acute stage to 32% of the normal level on the average. This may characterize the hemorrhagic diathesis of the DHF patients.

Keywords

alpha-2-Antiplasmin, Platelet Count, Fibrinolysis, Disseminated Intravascular Coagulation, Blood Coagulation Factors, Dengue, Fibrin Fibrinogen Degradation Products, Child, Preschool, Acute Disease, Humans, Blood Coagulation Tests, Child

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	20
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%