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European Neurology
Article . 2011 . Peer-reviewed
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Is Confrontation Naming Performance in Alzheimer’s Disease the Nominal Linguistic Retrogenesis of Normal Development?

Authors: Young H. Sohn; HyangHee Kim; Duk L. Na; Eun Jin Baek; Ji Hye Yoon; Ji E. Lee;

Is Confrontation Naming Performance in Alzheimer’s Disease the Nominal Linguistic Retrogenesis of Normal Development?

Abstract

We investigated confrontation naming performance of patients with Alzheimer’s disease (AD) and normal children (NC) to see if the nature of naming performance of AD patients is the reversal of that in normal development. Sixty items of the Boston Naming Test were given to 78 AD patients (and 40 age- and education-matched normal elderly) and 1,080 NC (3- to 14-year-olds). The analyses revealed that, firstly, the naming abilities of the AD patients demonstrated an inverse relationship with those of the NC. Secondly, from the clinical point of view, AD patients tended to lose vocabulary acquired later first while maintaining those acquired in earlier stages of development. Based on the findings, we claimed that this phenomenon was ‘a nominal retrogenesis’ in which ‘retrogenesis’ is ‘the process by which degenerative mechanisms reverse the order of acquisition in normal development’ as defined by Reisberg and colleagues.

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Keywords

Cognition Disorders/diagnosis, Male, Cognition Disorders/etiology*, Adolescent, Developmental Disabilities, 610, Developmental Disabilities/etiology*, Neuropsychological Tests, Severity of Illness Index, Vocabulary, Elderly, Alzheimer Disease, Alzheimer Disease/complications*, Linguistics*, Humans, Names, Preschool, Child, Verbal Learning/physiology, Children, Confrontation naming, Retrogenesis, Age Factors, Linguistics, Verbal Learning, Names*, Case-Control Studies, Child, Preschool, Regression Analysis, Female, Cognition Disorders, Alzheimer’s disease

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Average
Average
Average
Green