'Concomitant depression' (Begleitdepression) is a term proposed by us to signify presence of somatic illness plus depressiveness at the time in one individual. Headache patients form a main part of patients bearing concomitant depression. Depressiveness can be a sequela of headache, a causative factor of headache, as well as a modifying one. The more severe a headache syndrome is the more it tends to be associated with depressiveness. Cephalea patients are more depression-afflicted than migraine patients, women more than men, higher age group more than lower ones. We have denominated a special 'depressive headache syndrome of higher age groups' for its great frequency and clinical importance. Therapy has to take into account all the causative and accompanying factors at the time; thus to include antidepressant therapy (in a complex way, using drugs beside psychotherapy) together with all indicated further somatotropic headache therapy. As slogan: No either/or-therapy but a comprehensive therapy.