Nasal polyposis is a common clinical problem. The polyps commonly arise from the ethmoid sinuses and the etiology is still poorly understood. There is a connection between nasal polyps and asthma, cystic fibrosis and aspirin intolerance, but it is unclear whether there is a connection between nasal polyps and nasal hyperreactivity. The aim of this study was to investigate whether there is a connection between nasal hyperreactivity and nasal polyposis. Ten patients with nasal polyposis entered the trial. The nasal reactivity was studied with rhinostereometry during provocation with histamine. It was found that the patients with polyps did not have any nasal hyperreactivity.