Calcium Transport in the Endolymphatic Sac
Copyright policy )Calcium Transport in the Endolymphatic Sac
Ca++ activity and DC potential were measured in vivo in the endolymphatic sac (ES) of guinea pigs by means of double-barrelled ion-sensitive microelectrodes. We found a positive DC potential of 14 mV and a Ca++ activity of 4.7 X 10(-4) M. Anoxia induced a decrease in the DC potential and an increase in Ca++ activity; however, no negative DC potential was measured during permanent anoxia. The Ca++ activity measured was in agreement with the Ca++ value calculated with the Nernst equation, assuming a positive DC potential. On the basis of these data, it was suggested that the Ca++ in the ES is in electrochemical equilibrium with the surrounding fluid and no active Ca++ transport is necessary in the ES of guinea pigs.
- Düsseldorf University Hospital Germany
Ion Exchange, Endolymph, Ear, Inner, Guinea Pigs, Electrochemistry, Animals, Biological Transport, Calcium, Endolymphatic Sac, Hypoxia, Microelectrodes
Ion Exchange, Endolymph, Ear, Inner, Guinea Pigs, Electrochemistry, Animals, Biological Transport, Calcium, Endolymphatic Sac, Hypoxia, Microelectrodes
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