
doi: 10.1159/000260442
pmid: 6927971
The bioavailability of fluoride (F) from NaF and Na2PO3F dentifrices was studied in detail in young volunteers. The method used was based on a comparison of plasma and urinary data obtained following intravenous administration of a single 3-mg dose F and ingestion of 6 g (6 mg F) of two different F dentifrices on three separate occasions. The plasma data indicated a higher degree of F bioavailability from the NaF dentifrice (111 ± 13%, SD, n = 4) as compared with theNa2P03F dentifrice (96 ± 16%, SD, n = 4). Since the absorption of F from the F dentifrices was essentially total it is concluded that F dentifrices may play an important part in the daily exposure of children to F.
Fluorides, Injections, Intravenous, Administration, Oral, Biological Availability, Humans, Dentifrices, Absorption
Fluorides, Injections, Intravenous, Administration, Oral, Biological Availability, Humans, Dentifrices, Absorption
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