descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1986 English Publisher:S. Karger AGJournal:Dermatology, volume 172, pages 191-195 (issn: 1018-8665, eissn: 1421-9832,

Authors: F. J. W. ten Kate; Arnold P. Oranje; E. Stolz; T. Van Joost; G. Dzoljic-Danilovic; E. C. Van Reede; V.D. Vuzevski;

doi: 10.1159/000249333

pmid: 2940127

Infantile Seborrheic Dermatitis

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Abstract

The pathomechanisms of infantile seborrheic dermatitis (ISD) are unknown. An allergic reaction to candidal antigens is one of the hypotheses. The skin of 6 patients suffering from ISD was studied by immunostaining techniques. The lymphocytic infiltrate was composed of Leu4-reactive T cells in which Leu3a-reactive (helper/inducer) cells predominated. Direct immunofluorescence studies revealed no significant deposits of immunoglobulins or complement factors. No candidal antigens could be demonstrated, either in epidermis or in dermis, although Candida species were cultured from different sites in 4 of the 6 patients.

Related Organizations

Erasmus University Rotterdam
Netherlands

Keywords

Immunoenzyme Techniques, Male, Immune Sera, Fluorescent Antibody Technique, Humans, Infant, Female, Lymphocytes, Dermatitis, Seborrheic, Skin

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