Peripheral Blood Cell Repopulation Following High-Dose Cyclophosphamide

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1992 English Publisher:S. Karger AGJournal:Chemotherapy, volume 38, pages 267-270 (issn: 0009-3157, eissn: 1421-9794,

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Authors: G, Codacci-Pisanelli; F, Franchi; A, Afeltra; F, Simone; L, Bonomo;

doi: 10.1159/000239010

pmid: 1473366

Peripheral Blood Cell Repopulation Following High-Dose Cyclophosphamide

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Abstract

High-dose cyclophosphamide can be used to obtain haematological stem cells from the peripheral blood. In this paper we analyse the dynamics of appearance of cells with these characteristics, together with the impact of this drug on the immunological system. Cyclophosphamide seems to possess immunomodulating effects even at high doses.

Related Organizations

Sapienza University of Rome
Italy
Roma Tre University
Italy

Keywords

Immune System, Antineoplastic Combined Chemotherapy Protocols, Humans, Breast Neoplasms, Female, Middle Aged, Hematopoietic Stem Cells, Cyclophosphamide, Melphalan

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