Delayed Type Hypersensitivity to Bovine Serum Albumin and to Lipid-Conjugated Bovine Serum Albumin in Mice

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1979 English Publisher:S. Karger AGJournal:International Archives of Allergy and Immunology, volume 59, pages 28-33 (issn: 1018-2438, eissn: 1423-0097,

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Authors: G, Drach; J, Chen-Marotel;

doi: 10.1159/000232236

pmid: 447404

Delayed Type Hypersensitivity to Bovine Serum Albumin and to Lipid-Conjugated Bovine Serum Albumin in Mice

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Abstract

Delayed type hypersensitivity (DTH) to bovine serum albumin (BSA) and to lipid-conjugated BSA were studied comparatively. Unlike the case of BSA with which no DTH can be detected with native antigen, injection of butyric-conjugated BSA (Bu-BSA) in sensitized mice provokes a typical DTH for an early and limited period. Alum-precipitated Bu-BSA (Al-Bu-BSA) provokes from the beginning a stronger DTH which persists a much longer period.

Keywords

Freund's Adjuvant, Serum Albumin, Bovine, Lipids, Butyrates, Mice, Alum Compounds, Animals, Cattle, Female, Hypersensitivity, Delayed

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