Procoagulant Activity of Activated Monocytes

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1977 English Publisher:S. Karger AGJournal:Pathophysiology of Haemostasis and Thrombosis, volume 6, pages 347-350 (issn: 1424-8832, eissn: 1424-8840,

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Authors: E, Hiller; J G, Saal; G, Riethmüller;

doi: 10.1159/000214201

pmid: 346452

Procoagulant Activity of Activated Monocytes

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Abstract

Endotoxin-stimulated monocytes develop a very high tissue-factor-like activity as compared to an equivalent number of monocytes in a preparation of monocyte-enriched mononuclear blood cells obtained by Ficoll®-Urovison® density gradient centrifugation which is not exposed to endotoxin. In monocytes which were obtained by plastic adherence from the monocyteenriched mononuclear blood cells, the tissue factor activity was as high as in the endotoxin-stimulated monocytes.

Keywords

Salmonella enteritidis, Bacterial Toxins, Cell Adhesion, Centrifugation, Density Gradient, Humans, Cell Separation, Monocytes, Thromboplastin

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