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Epsilon-Aminocaproic Acid Myopathy

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1982Publisher:S. Karger AGJournal:European Neurology, volume 21, pages 242-248 (issn: 0014-3022, eissn: 1421-9913,

Authors: J.A.L. Vanneste; G.K. van Wijngaarden;

doi: 10.1159/000115487

pmid: 7117311

Epsilon-Aminocaproic Acid Myopathy

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Abstract

A case of acute necrotic myopathy due to epsilon-aminocaproic acid (EACA) is described and compared with similar cases in the literature. This myopathy has only been noted after prolonged administration of the drug. The pathogenesis of this necrotic myopathy remains unclear, but our finds did not support a muscular vasculitis or an autoimmune reaction. Systematic preventive measures in patients with prolonged EACA therapy are proposed.

Related Organizations

University of Amsterdam
Netherlands

Keywords

Adult, Aminocaproates, Male, Electromyography, Biopsy, Muscles, Myoglobinuria, Neuromuscular Diseases, Subarachnoid Hemorrhage, Necrosis, Aminocaproic Acid, Humans

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	20
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average