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The Genomic Approach to Growth Prediction

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2007 United Kingdom English Publisher:S. Karger AGJournal:Hormone Research in Paediatrics, volume 67, pages 10-15 (issn: 1663-2818, eissn: 1663-2826,

Authors: Clayton, P. E.; Whatmore, A. J.;

doi: 10.1159/000097544

The Genomic Approach to Growth Prediction

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Abstract

<i>Background:</i> A major objective when using recombinant human growth hormone (rhGH) in childhood is to attain the maximum sustained growth response that can be achieved in an individual child while avoiding adverse events and ensuring that biomarkers of response, such as insulin-like growth factor I (IGF-I), remain within acceptable limits. <i>Conclusion:</i> In practice, this is currently achieved by titrating GH dose against growth rate and serum IGF-I concentration.

Country

United Kingdom

Related Organizations

University of Salford
United Kingdom

Keywords

Small-for-gestational age, Growth hormone receptor, Turner syndrome, Growth hormone deficiency, Insulin-like growth factor I

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	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average