Patient Selection for IGF-I Therapy
Copyright policy )Patient Selection for IGF-I Therapy
• Many patients previously classified as 'idiopathic short stature' have Primary IGFD. In some studies, this number is as high as 50%. • For patients with severe Primary IGFD, treatment of choice should be IGF-I, either alone or in combination with IGFBP-3. • For patients with Primary IGFD due to defects of the IGF-I gene, IGF-I (alone) is the treatment of choice. • For patients with milder forms of Primary IGFD, the relative advantages of therapy with IGF-I vs. GH need further evaluation.
- University of Salford United Kingdom
Male, Hormone Replacement Therapy, Patient Selection, methods: Hormone Replacement Therapy, drug therapy: Growth Disorders, deficiency: Insulin-Like Growth Factor I, Insulin-Like Growth Factor Binding Protein 3, therapeutic use: Insulin-Like Growth Factor Binding Protein 3, Growth Hormone, Humans, Female, therapeutic use: Growth Hormone, Insulin-Like Growth Factor I, Growth Disorders
Male, Hormone Replacement Therapy, Patient Selection, methods: Hormone Replacement Therapy, drug therapy: Growth Disorders, deficiency: Insulin-Like Growth Factor I, Insulin-Like Growth Factor Binding Protein 3, therapeutic use: Insulin-Like Growth Factor Binding Protein 3, Growth Hormone, Humans, Female, therapeutic use: Growth Hormone, Insulin-Like Growth Factor I, Growth Disorders
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