Co(II) and Ni(II) complexes with a Schiff base, N‐(2‐furanylmethylene)‐2‐aminothiadiazole have been prepared and characterized by their physical, spectral and analytical data. The synthesized Schiff‐bases act as tridentate ligands during the complexation reaction with Co(II) and Ni(II. metal ions. They possess the composition [M(L)2]Xn (where M=Co(II) or Ni(II), L=, X= , , or and n=1 or 2) and show an octahedral geometry. In order to evaluate the effect of anions upon chelation, the Schiff‐base and its complexes have been screened for antibacterial activity against bacterial strains e.g., Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa.