Aim: This study investigates the impact of strength‐based leadership (SBL) on fostering AI‐driven job crafting to enhance patient care and nurse creativity in the context of Society 5.0. Background: The emergence of Society 5.0 emphasises a human‐centred approach to technological integration, posing opportunities and challenges for nursing management. The increasing reliance on digital technologies necessitates that nurses update their skills and adapt to new systems, potentially compromising the quality of care and personal connections with patients. Methods: A cross‐sectional descriptive study design was employed to target nurses in tertiary hospitals in Henan province, China. The sample size was determined using G∗power software, accounting for a projected dropout rate. The structural equation modelling approach was adopted to analyse the collected data. Results: The results show that SBL has positively promoted AI‐driven crafting (task, relational and cognitive). Furthermore, the outcomes highlight that AI‐driven job crafting positively promotes patients’ quality of care. Surprisingly, the findings indicate that AI‐driven job crafting (task and cognitive) has an insignificant relationship with nursing creativity. Conclusion: By elucidating the role of SBL in promoting AI‐driven job crafting, this research aims to provide insights into effective nursing management strategies that leverage technological advancements while maintaining high standards of patient care. Implications for Nursing Management: The findings highlight the importance of leadership focussing on employee strengths. This fosters an environment conducive to innovation and improved patient outcomes in a rapidly evolving healthcare landscape.