
pmid: 28900467
pmc: PMC5576399
We show that many structured epidemic models may be described using a straightforward product structure in this paper. Such products, derived from products of directed graphs, may represent useful refinements including geographic and demographic structure, age structure, gender, risk groups, or immunity status. Extension to multistrain dynamics, that is, pathogen heterogeneity, is also shown to be feasible in this framework. Systematic use of such products may aid in model development and exploration, can yield insight, and could form the basis of a systematic approach to numerical structural sensitivity analysis.
Bioinformatics, Applied Mathematics, Biomedical Engineering, Populations and Evolution (q-bio.PE), Biological, Applied mathematics, Quantitative Biology - Quantitative Methods, Models, Biological, Mathematical Sciences, Engineering, Models, FOS: Biological sciences, Humans, Quantitative Biology - Populations and Evolution, Epidemiologic Methods, Biomedical engineering, Quantitative Methods (q-bio.QM), Research Article
Bioinformatics, Applied Mathematics, Biomedical Engineering, Populations and Evolution (q-bio.PE), Biological, Applied mathematics, Quantitative Biology - Quantitative Methods, Models, Biological, Mathematical Sciences, Engineering, Models, FOS: Biological sciences, Humans, Quantitative Biology - Populations and Evolution, Epidemiologic Methods, Biomedical engineering, Quantitative Methods (q-bio.QM), Research Article
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