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Computational and Mathematical Methods in Medicine
Article . 2012 . Peer-reviewed
License: CC BY
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Article . 2012
License: CC BY
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zbMATH Open
Article . 2012
Data sources: zbMATH Open
DBLP
Article . 2012
Data sources: DBLP
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A Meshfree Method for Simulating Myocardial Electrical Activity

A meshfree method for simulating myocardial electrical activity
Authors: Heye Zhang; Huajun Ye; Wenhua Huang;

A Meshfree Method for Simulating Myocardial Electrical Activity

Abstract

An element-free Galerkin method (EFGM) is proposed to simulate the propagation of myocardial electrical activation without explicit mesh constraints using a monodomain model. In our framework the geometry of myocardium is first defined by a meshfree particle representation that is, a sufficient number of sample nodes without explicit connectivities are placed in and inside the surface of myocardium. Fiber orientations and other material properties of myocardium are then attached to sample nodes according to their geometrical locations, and over the meshfree particle representation spatial variation of these properties is approximated using the shape function of EFGM. After the monodomain equations are converted to their Galerkin weak form and solved using EFGM, the propagation of myocardial activation can be simulated over the meshfree particle representation. The derivation of this solution technique is presented along a series of numerical experiments and a solution of monodomain model using a FitzHugh-Nagumo (FHN) membrane model in a canine ventricular model and a human-heart model which is constructed from digitized virtual Chinese dataset.

Related Organizations
Keywords

Models, Anatomic, myocardial electrical activity, Databases, Factual, Physiology (general), Finite Element Analysis, Finite element, Rayleigh-Ritz and Galerkin methods for boundary value problems involving PDEs, Membrane Potentials, Diffusion, Dogs, Heart Conduction System, Animals, Humans, Computer Simulation, Models, Statistical, Myocardium, Models, Cardiovascular, Computational Biology, Myocardial Contraction, Electrophysiology, element-free Galerkin method, Algorithms, Research Article

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Average
Average
Average
Green
gold