Combining the color difference formula of CIEDE2000 and the printing industry standard for visual verification, we present an objective color image quality assessment method correlated with subjective vision perception. An objective score conformed to subjective perception (OSCSP)Qwas proposed to directly reflect the subjective visual perception. In addition, we present a general method to calibrate correction factors of color difference formula under real experimental conditions. Our experiment results show that the present DE2000-based metric can be consistent with human visual system in general application environment.