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Syntheses, Characterization and Biological Activity of Some 1, 2, 4‐Triazole Derivatives

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2009 English Publisher:WileyJournal:Journal of Chemistry, volume 6, pages 796-800 (issn: 2090-9063, eissn: 2090-9071,

Authors: R. J. Singh; D. K. Singh;

doi: 10.1155/2009/419214

Syntheses, Characterization and Biological Activity of Some 1, 2, 4‐Triazole Derivatives

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Abstract

Syntheses of a series of 3‐alkyl‐4‐ amino‐5‐ cyanomethyl‐4H‐1, 2, 4‐triazoles with active methylene groups are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa. All the compounds carrying 1, 2, 4‐ triazole moiety showed significant biological activity.

Keywords

Chemistry, QD1-999

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