
Novel genetic findings about papillary thyroid carcinoma identify BRAF gene as a subject of great interest. Involvement of BRAF gene in pathogenesis of PTC, diagnostic value and the putative prognostic significance of its T1799A mutation are summarized in this article. Furthermore, a particular attention is focused to the role of pre‐operative detection of BRAF mutation in the FNAB specimens of thyroid nodules and to the use of this gene as target for an effective cancer therapy.
Proto-Oncogene Proteins B-raf, QH573-671, DNA Mutational Analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Carcinoma, Papillary, Mutation, Animals, Humans, Other, Thyroid Neoplasms, Cytology, RC254-282
Proto-Oncogene Proteins B-raf, QH573-671, DNA Mutational Analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Carcinoma, Papillary, Mutation, Animals, Humans, Other, Thyroid Neoplasms, Cytology, RC254-282
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 11 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
