
pmid: 23636261
Nogo-A was initially discovered as a myelin-associated growth inhibitory protein limiting axonal regeneration after central nervous system (CNS) injury. This review summarizes current knowledge on how myelin and neuronal Nogo-A and its receptors exert physiological functions ranging from the regulation of growth suppression to synaptic plasticity in the developing and adult intact CNS.
Central Nervous System, Neurons, Neuronal Plasticity, 10242 Brain Research Institute, Nogo Proteins, 610 Medicine & health, Receptors, Cell Surface, 1314 Physiology, Synaptic Transmission, Nerve Regeneration, 570 Life sciences; biology, Animals, Humans, Trauma, Nervous System, Myelin Proteins, Myelin Sheath
Central Nervous System, Neurons, Neuronal Plasticity, 10242 Brain Research Institute, Nogo Proteins, 610 Medicine & health, Receptors, Cell Surface, 1314 Physiology, Synaptic Transmission, Nerve Regeneration, 570 Life sciences; biology, Animals, Humans, Trauma, Nervous System, Myelin Proteins, Myelin Sheath
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